10 Best Hyaluronic Acid Serums, According to Dermatologists 2024


After topping our list of best serums for dry skin, La Roche-Posay’s Hyalu-B5 Serum continues to reign supreme. So what exactly makes this drugstore serum so great? There’s the sophisticated formula, to start. Margarita Lolis, MD, a board-certified dermatologist and Mohs surgeon, points to the two different types of hyaluronic acid present in the serum—one high molecular weight, one low—which ensure deep hydration and moisture within the skin. There’s also the vitamin B5, which acts as both a humectant and an emollient, drawing water to the skin, then sealing that moisture as well as madecassoside, more commonly known as centella asiatica, to soothe redness and irritation. For Jodi LoGerfo, MD, a doctor of nursing practice and family nurse practitioner certified in family medicine and dermatology, the appeal lies in its immediate effects, leaving skin feeling moist, plumped, and hydrated. And, of course, there’s the sheer accessibility to contend with: Not only is the noncomedogenic formula cost effective, but it’s also available at most drugstores.

Size: 1.01 oz. / Key ingredients: Hyaluronic acid, madecassoside, glycerin, vitamin B5 / Skin types: All

  • What we like: Effectively smooths, soothes, strengthens, and repairs dry, tight skin with a sophisticated but widely accessible formula
  • What could be improved: The price is on the higher side for a drugstore pick.





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